Rockefeller University

SIRT1 takes down tumors

Yuan et al. have identified another anti-cancer effect of the "longevity" protein SIRT1. By speeding the destruction of the tumor promoter c-Myc, SIRT1 curbs cell division. The study will be published online ...

Apr 13, 2009 4.6 / 5 (5) 0

HIV pays a price for invisibility

Mutations that help HIV hide from the immune system undermine the virus's ability to replicate, show an international team of researchers in the April 13 issue of the Journal of Experimental Medicine. The study was publis ...

Apr 13, 2009 3 / 5 (4) 1

When cancer cells can't let go

Like a climber scaling a rock face, a migrating cancer cell has to keep a tight grip on the surface but also let go at the right moment to move ahead. Chan et al. reveal that the focal adhesion kinase (FAK) ...

Apr 13, 2009 3 / 5 (1) 0

Turn back, wayward axon

To a growing axon, the protein RGMa is a "Wrong Way" sign, alerting it to head in another direction. As Hata et al. demonstrate in the March 9, 2009 issue of the Journal of Cell Biology, translating that s ...

Mar 09, 2009 4.5 / 5 (2) 0