DNA duplications may be responsible for genomic-based diseases

Dec 28, 2011

An important part of saving a species is often understanding its DNA. Through a collaborative effort including 14 scientists representing organizations across Europe and the United States, researchers have been able to analyze the genome of the great ape species of the world.

"A robust appreciation of the means and methods of the evolution of genomes which underlies the diversification of the great apes requires a more detailed knowledge of genome variation that is poorly revealed by current methods. " said Oliver Ryder Ph.D., Director of Genetics for Global's Institute of Conservation Research. "This article represents an international collaboration that provides a new level of understanding of the evolutionary dynamics of relatively small DNA duplications that, in humans - and likely great apes as well - may be contributing factors to "genomic" diseases, that in include autism and mental retardation."

The study, published in the August issue of Genome Research, highlights the areas of DNA that appear to be most closely shared by different species. Of particular note is the fact that bonobo and chimpanzee DNA share more with gorilla than expected.

Explore further: New concepts based on advances in animal systematics

Provided by Zoological Society of San Diego

3 /5 (1 vote)
add to favorites email to friend print save as pdf

Related Stories

Treaty: last chance to save great apes

Sep 12, 2005

A treaty signed during the weekend in the Democratic Republic of Congo reportedly might be the world's last chance to save great apes from extinction.

New genome sequencing targets announced

Jul 24, 2006

The U.S. National Human Genome Research Institute has announced several new sequencing targets, including the northern white-cheeked gibbon.

Counting duplicated genome segments now possible

Aug 30, 2009

(PhysOrg.com) -- A newly designed computational method has proven its usefulness in counting copies of duplicated genome sequences and in doing initial assessments of their contents, according to a study to be published Aug. ...

Johns Hopkins to participate in 1000 Genomes Project

Jan 22, 2008

Researchers at the McKusick-Nathans Institute of Genetic Medicine (IGM) at Johns Hopkins will join other national and international scientists in the 1000 Genomes Project, an ambitious effort that will involve sequencing ...

Recommended for you

Iberian pig genome remains unchanged after five centuries

11 hours ago

A team of Spanish researchers have obtained the first partial genome sequence of an ancient pig. Extracted from a sixteenth century pig found at the site of the Montsoriu Castle in Girona, the data obtained indicates that ...

New concepts based on advances in animal systematics

14 hours ago

The way in which most multicellular organisms have been classified has been the same for more than a century. Only recently have scientists developed the tools and knowledge to question the way we classify ...

New dawn for pasta wheat in Australia

17 hours ago

The University of Adelaide's durum breeding program today at the Hart Field Day will release a new durum wheat variety called DBA-Aurora which promises a step-change in potential durum production in southern Australia.

User comments : 0