DNA duplications may be responsible for genomic-based diseases

December 28, 2011

An important part of saving a species is often understanding its DNA. Through a collaborative effort including 14 scientists representing organizations across Europe and the United States, researchers have been able to analyze the genome of the great ape species of the world.

"A robust appreciation of the means and methods of the evolution of genomes which underlies the diversification of the great apes requires a more detailed knowledge of genome variation that is poorly revealed by current methods. " said Oliver Ryder Ph.D., Director of Genetics for Global's Institute of Conservation Research. "This article represents an international collaboration that provides a new level of understanding of the evolutionary dynamics of relatively small DNA duplications that, in humans - and likely great apes as well - may be contributing factors to "genomic" diseases, that in include autism and mental retardation."

The study, published in the August issue of Genome Research, highlights the areas of DNA that appear to be most closely shared by different species. Of particular note is the fact that bonobo and chimpanzee DNA share more with gorilla than expected.

Explore further: World ape population dwindles at fast rate

Related Stories

Treaty: last chance to save great apes

September 12, 2005

A treaty signed during the weekend in the Democratic Republic of Congo reportedly might be the world's last chance to save great apes from extinction.

New genome sequencing targets announced

July 24, 2006

The U.S. National Human Genome Research Institute has announced several new sequencing targets, including the northern white-cheeked gibbon.

Johns Hopkins to participate in 1000 Genomes Project

January 22, 2008

Researchers at the McKusick-Nathans Institute of Genetic Medicine (IGM) at Johns Hopkins will join other national and international scientists in the 1000 Genomes Project, an ambitious effort that will involve sequencing ...

Counting duplicated genome segments now possible

August 30, 2009

(PhysOrg.com) -- A newly designed computational method has proven its usefulness in counting copies of duplicated genome sequences and in doing initial assessments of their contents, according to a study to be published Aug. ...

Recommended for you

Research reveals new clues about how humans become tool users

October 7, 2015

New research from the University of Georgia department of psychology gives researchers a unique glimpse at how humans develop an ability to use tools in childhood while nonhuman primates—such as capuchin monkeys and chimpanzees—remain ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.