Genome Biology

X chromosome inactivation

Each cell in a woman's body contains two X chromosomes. One of these chromosomes is switched off, because nobody can live with two active X chromosomes. Hendrik Marks and Henk Stunnenberg, molecular biologists at Radboud ...

dateAug 19, 2015 in Biotechnology
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Kiwi bird genome sequenced

Its unusual biological characteristics make the flightless kiwi a unique kind of bird. Researchers of the University of Leipzig and the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, have now sequenced ...

dateJul 22, 2015 in Plants & Animals
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Sex chromosomes—why the Y genes matter

Several genes have been lost from the Y chromosome in humans and other mammals, according to research published in the open access journal Genome Biology. The study shows that essential Y genes are rescued by relocating to ...

dateMay 27, 2015 in Biotechnology
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Highly efficient CRISPR knock-in in mouse

Genome editing using CRISPR/Cas system has enabled direct modification of the mouse genome in fertilized mouse eggs, leading to rapid, convenient, and efficient one-step production of knockout mice without embryonic stem ...

dateMay 01, 2015 in Biotechnology
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