Why transporters really matter for cell factories

In a new study published in PNAS, scientists from The Novo Nordisk Foundation Center for Biosustainability (DTU Biosustain) explored how different cell membrane transporters impact the production of dicarboxylic acids.

From bugs to drugs

A new study led by Prof Shoumo Bhattacharya has decoded the structure of unique proteins found in tick saliva and created new ones not found in nature, paving the way for a new generation of "Swiss-army knife' anti-inflammatory ...

Freeze frame: Researchers solve how cells unfold proteins

A happy cell is a balanced cell, but for every stupendously twisted protein it creates, it must tear the old ones asunder. That means untangling a convoluted pretzel-like mass for recycling. Cdc48 plays a critical role in ...

How the cell protects itself

The cell contains transcripts of genetic material, which migrate from the cell nucleus to another part of the cell. This movement protects the genetic transcripts from the recruitment of "spliceosomes." If this protection ...

Screening for genes to improve protein production in yeast

By silencing genes, researchers have managed to increase protein production in yeast significantly. This method can lay the grounds for engineering better yeast production hosts for industries producing biopharmaceutical ...

Molecular biologists compared human and yeast FACT

A protein complex called facilitates chromatin transcription (FACT) plays a role in DNA packing within a nucleus, as well as in oncogenesis. A team of scientists from MSU, working in cooperation with foreign colleagues, have ...

How a cell knows when to divide

How does a cell know when to divide? We know that hundreds of genes contribute to a wave of activity linked to cell division, but to generate that wave new research shows that cells must first grow large enough to produce ...

A brewer's tale of proteins and beer

The transformation of barley grains into beer is an old story, typically starring water, yeast and hops. Now, in a report in the Journal of Proteome Research, scientists are highlighting another character in this tale: proteins. ...

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