Our genomic DNA is continuously damaged by endogenous factors such as reactive oxygen species, and also by environmental factors such as ultraviolet light, radiation, and chemicals. Failure to repair damaged DNA may induce ...
Molecular & Computational biology
Jun 12, 2023
0
31
Nucleotide excision repair (NER) is a major conserved DNA repair pathway, which repairs various types of damage in the genome, such as those induced by ultraviolet light and environmental agents. Dysfunction in this pathway ...
Cell & Microbiology
Sep 27, 2022
0
95
When cells reproduce, the internal mechanisms that copy DNA get it right nearly every time. Rice University bioscientists have uncovered a tiny detail that helps understand how the process could go wrong.
Cell & Microbiology
May 9, 2022
0
368
Sometimes, when something is broken, the first step to fixing it is to break it even more.
Biotechnology
Jun 22, 2020
0
27
In the time it takes you to read this sentence, every cell in your body suffers some form of DNA damage. Without vigilant repair, cancer would run rampant, and now scientists at the University of Pittsburgh have gotten a ...
Molecular & Computational biology
Jul 22, 2019
3
384
The first line of defense against skin cancer is the ability to repair DNA damage caused by UV light. The XPA protein plays an important role in the repair of certain DNA damage, and mutations in this protein have been implicated ...
Biochemistry
Dec 7, 2017
0
3
The severe and debilitating genetic disease Xeroderma pigmentosum impedes cells to repair UV-induced DNA damage. Scientists from CeMM found a drug approved for diabetes treatment to alleviate the impact of the gene defect ...
Cell & Microbiology
Nov 20, 2017
0
3
