Researchers improve fitness of cells used in cell transplants

A readily available, inexpensive, small molecule drug can improve the fitness of hematopoietic stem and progenitor cells (HSPCs) that are modified outside the body, potentially improving the success of procedures such as ...

Revealing the dynamic choreography inside multilayer vesicles

Our cells and the machinery inside them are engaged in a constant dance. This dance involves some surprisingly complicated choreography within the lipid bilayers that comprise cell membranes and vesicles—structures that ...

Studying cellular deliveries

Many cells, including cancer cells, are known to secrete short RNAs in tiny vesicles, which then move inside other cells—potentially a form of cell-to-cell communication.

Regulators for extracellular vesicle production

Biological vesicles are nano-sized containers that transport proteins and other substances within or between cells. Most cells release so-called extracellular vesicles (EVs), which play important roles in cell-to-cell communication. ...

Division and growth of synthetic vesicles

One big challenge for the production of synthetic cells is that they must be able to divide to have offspring. In the journal Angewandte Chemie, a team from Heidelberg has now introduced a reproducible division mechanism ...

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