The endoplasmic reticulum (ER) is a major organelle responsible for protein folding and trafficking. Protein folding stress in the ER can lead to the accumulation of unfolded or misfolded proteins, known as ER stress, which ...
Cell & Microbiology
Jun 25, 2024
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18
Scientists at Nanyang Technological University, Singapore (NTU Singapore) have found that a stress response in cells, when "switched on" at a post-reproductive age, could be the key to slow down aging and promote longevity.
Cell & Microbiology
Oct 19, 2022
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166
Scientists at the University of Leeds have developed an approach that could help in the design of a new generation of synthetic biomaterials made from proteins.
Bio & Medicine
Jul 6, 2021
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33
Planarians are able to survive long periods of starvation unscathed by maintaining their stem cell pool and regenerative capacity. The molecular processes behind this are not yet known. Jena researchers from the Leibniz Institute ...
Cell & Microbiology
Jul 1, 2021
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14
Environmental extremes driven by climate change create stresses in crops, and plant breeders are attempting to untangle the genetic factors that endow plants with tolerance to stress. A new study from Iowa State University ...
Plants & Animals
Aug 27, 2020
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28
There is a broad range of mechanisms associated with chemoresistance, many of which to date are only poorly understood. The so-called cellular stress response—a set of genetic programs that enable the cells to survive under ...
Cell & Microbiology
Jun 10, 2020
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141
Viruses are intracellular parasites that cause disease by infecting the cells in the body and, in a study published today in Nature Microbiology, researchers at Children's Hospital of Pittsburgh of UPMC and the University ...
Cell & Microbiology
Mar 12, 2018
1
130
Durable proteins make life possible in the crushing depths of the ocean, and may have evolved in life below the surface of ice-bound oceanic exo-planets. These proteins stay folded - allowing them to perform their function—under ...
Biochemistry
Feb 10, 2017
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588
When a large protein unfolds in transit through a cell, it slows down and can get stuck in traffic. Using a specialized microscope—a sort of cellular traffic camera—University of Illinois chemists now can watch the way ...
Cell & Microbiology
Dec 9, 2014
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0
Living cells are like miniature factories, responsible for the production of more than 25,000 different proteins with very specific 3-D shapes. And just as an overwhelmed assembly line can begin making mistakes, a stressed ...
Cell & Microbiology
Sep 11, 2014
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0
