New protein identified in bacterial arsenal

(PhysOrg.com) -- Nearly a billion years ago, bacteria evolved an insidious means of infecting their hosts — a syringe-like mechanism able to inject cells with stealthy hijacker molecules. These molecules, called virulence ...

How cellular machinery labels proteins for degradation

Proteins are molecular work horses in the cell that perform specific tasks, but it is essential that the timing of protein activities is exquisitely controlled. When proteins have fulfilled their tasks, their degradation ...

Researchers discover molecular light switch in photoreceptor cells

How our eyes detect and respond to changes in light intensity is determined by specialized cells in the eye called photoreceptors. In addition to converting light into electrical signals, effectively allowing us to see, rod-shaped ...

Preventing resistance in cancer therapy

The latest developmental drugs, particularly for use in oncology, rely on the targeted degradation of harmful pathogenic proteins. In a recent study published in Nature Chemical Biology, researchers at CeMM, the Research ...

New insights into ubiquitin signalling

Scientists at the University of Würzburg have generated new insights into the intricate molecular underpinnings of ubiquitin signaling. Their results may provide new avenues for cancer therapy.

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