Immunotherapy's promise in the fight against cancer drew international attention after two scientists won a Nobel Prize this year for unleashing the ability of the immune system to eliminate tumor cells.
Bio & Medicine
Jan 21, 2019
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381
DNA-damaging agents, or "DDAs," make up the most widely used group of cancer drugs. Yet their therapeutic success has been curtailed by drug resistance—either present in cancer cells from the disease onset or arising during ...
Molecular & Computational biology
Oct 29, 2018
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48
Programming the body's immune system to attack cancer cells has had promising results for treating blood cancers such as lymphoma and leukemia. This tactic has proven more challenging for solid tumors such as breast or lung ...
Bio & Medicine
Jul 9, 2018
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157
Ishan Deshpande and his colleagues from the group of Susan Gasser and the Protein Structure Facility at the FMI elucidated the mechanism of how Mec1-Ddc2, a tumor suppressor involved in DNA damage response assembles at sites ...
Cell & Microbiology
Oct 16, 2017
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68
A drug-like molecule developed by Duke Health researchers appears to intercede in an inflammatory response that is at the center of a variety of diseases, including some cancers, rheumatoid arthritis and Crohn's disease.
Biochemistry
Aug 17, 2017
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4
In the battle against cancer, which kills nearly 8 million people worldwide each year, doctors have in their arsenal many powerful weapons, including various forms of chemotherapy and radiation. What they lack, however, is ...
Analytical Chemistry
Aug 5, 2015
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1446
Scientists have found a way to sneak nanoparticles carrying tumor-fighting drugs past cells of the immune system, which would normally engulf the particles, preventing them from reaching their target. The technique takes ...
Bio & Medicine
Jul 17, 2013
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0
(Phys.org) —Activating the body's immune system to attack cancer and prevent it from recurring is one of the Holy Grails of cancer research because of its ability to specifically target cancer and to search almost anywhere ...
Bio & Medicine
Jul 15, 2013
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0
(Phys.org) —German researchers have developed a scheme for the preparation of nanoparticles that offer a highly versatile system for targeted drug delivery directly into diverse types of tumor cells.
Bio & Medicine
May 29, 2013
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0
A particular tumor suppressor gene that fights cancer cells does more than clamp down on unabated cell division—the hallmark of the disease—it also can help make cells more fit by allowing them to fend off stress, says ...
Cell & Microbiology
May 10, 2013
0
0
