Immunotherapy is promising for cancer treatment. The key to improving the therapeutic effect is to drive the patient's own immune system to produce a strong, effective, and enduring tumor-specific immune response. Engineered ...
Bio & Medicine
Oct 19, 2021
0
22
A new study reveals that high-grade gliomas, or brain tumors, in dogs contained more immune cells associated with suppressing immune response than low-grade gliomas. The work, which is the most extensive examination of immune ...
Veterinary medicine
Aug 19, 2021
0
6
A new synthetic protein nanoparticle capable of slipping past the nearly impermeable blood-brain barrier could deliver cancer-killing drugs directly to malignant brain tumors, new research from the University of Michigan ...
Bio & Medicine
Nov 10, 2020
0
807
One of the key challenges in developing effective, targeted cancer treatments is the heterogeneity of the cancer cells themselves. This variation makes it difficult for the immune system to recognize, respond to and actively ...
Bio & Medicine
Oct 2, 2020
0
646
Our immune system ought to be able to recognize and kill tumor cells. However, many tumors deceive the immune system. For example, they induce the so-called immune checkpoints of T-cells to shut down immune responses. In ...
Biochemistry
Jul 8, 2020
0
6
A protein derived from the saliva of the tick Amblyomma sculptum has been successfully used by researchers at the Butantan Institute in São Paulo, Brazil, to treat skin cancer (melanoma) in horses. The results of the study ...
Veterinary medicine
Jun 29, 2020
0
3
Researchers in the cancer nanomedicine community debate whether use of tiny structures, called nanoparticles, can best deliver drug therapy to tumors passively—allowing the nanoparticles to diffuse into tumors and become ...
Bio & Medicine
Mar 26, 2020
0
48
Theoretically, our immune system could detect and kill cancer cells. Unfortunately, tumors are well armed to fight these attacks. Despite modern cancer treatments, metastases and relapses remain a major problem. Increasing ...
Bio & Medicine
Oct 25, 2019
0
55
A new study led by Massachusetts General Hospital (MGH) investigators finds that radiation therapy may increase the uptake of therapeutic nanoparticles by glioblastomas, raising the possibility of using both growth-factor-targeted ...
Bio & Medicine
Mar 27, 2019
0
20
Researchers have engineered "antibody-like" T cell receptors that can specifically stick to cells infected with cytomegalovirus, or CMV, a virus that causes lifelong infection in more than half of all adults by age 40. These ...
Biochemistry
Feb 22, 2019
0
88
