In higher organisms, detection of DNA in the cytoplasm triggers an immune reaction. The enzyme that senses "misplaced" DNA is also found in the nucleus, but nuclear DNA has no such effect. LMU researchers now report why that ...
Molecular & Computational biology
Sep 11, 2020
0
32
A nanomedicine-based strategy for chemo-immunotherapy (CIT) of glioblastoma (GBM), which has the worst prognosis among brain tumors, was successfully developed. In vivo experiments demonstrated that the combined use of epirubicin-encapsulating ...
Bio & Medicine
Aug 7, 2020
0
9
Scripps Research chemists Hans Renata, Ph.D., and Alexander Adibekian, Ph.D., have discovered a way to efficiently create a synthetic version of a valuable natural compound called cepafungin I, which has shown promise as ...
Biochemistry
Aug 6, 2020
0
2982
Cell division is a fundamental process that organisms need to reproduce, grow, and make repairs. But when an error disrupts this complex biological process, cellular abnormalities can lead to diseases, such as cancer, where ...
Molecular & Computational biology
Jul 24, 2020
0
258
A unique nanoparticle to deliver a localized cancer treatment inhibits tumor growth in mice, according to a team of Penn State researchers.
Bio & Medicine
Jul 7, 2020
0
310
Magnetic nanoparticles, a class of nanoparticles that can be manipulated by magnetic fields, have a wide range of technical and biomedical applications, including magnetic hyperthermia, targeted drug delivery, new magnetic ...
Nanophysics
Jun 16, 2020
0
268
The gene p53 is extremely important in cell biology and, hence, the world of cell replacement therapy. Its role is to regulate the cell cycle and halt the formation of tumors, leading to its nickname the "tumor suppressor ...
Cell & Microbiology
Jun 1, 2020
0
1
For decades, scientists have explored the use of liposomes—hollow spheres made of lipid bilayers—to deliver chemotherapy drugs to tumor cells. But drugs can sometimes leak out of liposomes before they reach their destination, ...
Bio & Medicine
May 20, 2020
0
125
In regenerative medicine, an ideal treatment for patients whose muscles are damaged from lack of oxygen would be to invigorate them with an injection of their own stem cells.
Bio & Medicine
May 1, 2020
0
632
A first-of-its-kind nanoparticle-based in vivo imaging technique that may one day be used to help diagnose and even treat cancer has been developed by researchers collaborating from Michigan State, Johns Hopkins and Stanford ...
Bio & Medicine
Apr 29, 2020
0
232
