'Designer' tubulins help crack the tubulin code

Tubulin is a protein that plays a crucial role in the structure and function of cells. It is the main component of microtubules, which are long, hollow fibers that provide structural support, help the cell divide, give it ...

Tubulin inhibitor with a unique molecular mechanism of action

Researchers at the Paul Scherrer Institute PSI and the Italian Institute of Technology IIT have developed a novel substance that disables a protein in the cell skeleton, leading to cell death. In this way, substances of this ...

Cell cytoskeleton as target for new active agents

Through a unique combination of computer simulations and laboratory experiments, researchers at the Paul Scherrer Institute (PSI) have discovered new binding sites for active agents—against cancer, for example—on a vital ...

Scientists discover new anti-cancer molecule

A group of Moscow scientists has discovered and explained the activity mechanism of a new anti-cancer molecule—diphenylisoxazole. This molecule has been shown to be effective against human cancer cells. The research, published ...

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