It sounds like science fiction to suggest that every cell in the human body is occupied by a tiny genome-equipped organelle, with which we exist in symbiosis. But in actuality, eukaryotic life is dependent on mitochondria, ...
It is now possible to create complex, custom-designed transmembrane proteins from scratch, scientists report this week. The advance, led by molecular engineers at the University of Washington Institute for Protein Design, ...
Biochemistry
Mar 1, 2018
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479
The transmembrane protein 206 abbreviated as TMEM206 is an evolutionarily conserved chloride channel that underlies the ubiquitously expressed, proton-activated, outwardly rectifying anion currents. In a new report now published ...
Rice University scientists have succeeded in analyzing transmembrane protein folding in the same way they study the proteins' free-floating, globular cousins.
Cell & Microbiology
Jul 16, 2014
1
0
A "vicious cycle" produces mucus that protects uterine and pancreatic cancer cells and promotes their proliferation, according to researchers at Rice University. The researchers offer hope for a therapeutic solution.
Biochemistry
Sep 16, 2013
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0
In 2015, the first commercial nanopore DNA sequencing device was introduced by Oxford Nanopore Technologies. Based on a synthetically engineered transmembrane protein, nanopore sequencing allows long DNA strands to be channelled ...
Bio & Medicine
Dec 13, 2019
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144
Human white blood cells, known as leukocytes, swim using a newly described mechanism called molecular paddling, researchers report in the September 15th issue of Biophysical Journal. This microswimming mechanism could explain ...
General Physics
Sep 15, 2020
1
327
In humans, virtually every cell stores fat. However, patients with a rare condition called congenital lipodystrophy, which is often diagnosed in childhood, cannot properly store fat, which accumulates in the body's organs ...
Cell & Microbiology
Feb 25, 2022
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83
A machine-learning model from MIT researchers computationally breaks down how segments of amino acid chains determine a protein's function, which could help researchers design and test new proteins for drug development or ...
Biochemistry
Mar 25, 2019
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45
Mitochondria are organelles that are known for providing the energy currency that fuels chemical reactions within cells, but they are also involved in other important processes vital for cell health including the innate immune ...
Molecular & Computational biology
Mar 1, 2024
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