The ability to translate the genetic code into proteins is an essential step in all living organisms. A cornerstone of this molecular process is the ability of transfer RNA (tRNA) molecules to couple recognition of the genetic ...
Molecular & Computational biology
Oct 19, 2018
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The Y chromosome, which is found only in males, is difficult to decode even with the latest sequencing technologies. Among evolutionary biologists, the question as to which genes lie on the male sex chromosome and where they ...
Biotechnology
Oct 25, 2017
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A study from Massachusetts General Hospital (MGH) investigators has found a surprising role for what had been considered a nonfunctional "junk" RNA molecule: controlling the cellular response to stress. In their report in ...
Cell & Microbiology
Dec 15, 2016
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New research by scientists from the University of Chicago demonstrates that the enzyme ALKBH1 can remove molecular modifications from transfer RNA, causing a measurable effect on protein translation in the cell. The study, ...
Cell & Microbiology
Oct 13, 2016
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The structure of a bacterial RNA-binding protein has been determined in the act of modifying a molecule of RNA—an achievement that provides researchers with a unique view of the protein's function in action and could lead ...
Cell & Microbiology
Apr 21, 2016
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599
Researchers at ETH Zurich are decoding the structure of the large ribosomal subunit of the mitochondria at an atomic level, thereby providing insight into the molecular architecture of this ribosome with implications for ...
Biochemistry
Oct 8, 2014
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The so-called central dogma of molecular biology—that DNA makes RNA which makes protein—has long provided a simplified explanation for how genetic information is deciphered and translated in living organisms.
Cell & Microbiology
Sep 15, 2014
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The molecular machine that makes essential components of ribosomes – the cell's protein factories – is like a Swiss-army knife, researchers at the European Molecular Biology Laboratory (EMBL) in Heidelberg, Germany, and ...
Cell & Microbiology
Oct 24, 2013
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An analysis of enzymes that load amino acids onto transfer RNAs—an operation at the heart of protein translation—offers new insights into the evolutionary origins of the modern genetic code, researchers report. Their ...
Biotechnology
Aug 26, 2013
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A new study shows how complex biochemical transformations may have been possible under conditions that existed when life began on the early Earth. The study shows that RNA is capable of catalyzing electron transfer under ...
Biochemistry
May 19, 2013
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