Cell memory mechanism discovered

The cells in our bodies can divide as often as once every 24 hours, creating a new, identical copy. DNA binding proteins called transcription factors are required for maintaining cell identity. They ensure that daughter cells ...

A protein that extends life of yeast cells

To understand and control aging is the aspiration of many scientists. Researchers at the Biozentrum of the University of Basel have now discovered that the protein Gcn4 decreases protein synthesis and extends the life of ...

Scientists reveal how epigenetic changes in DNA are interpreted

A new study in Science from Karolinska Institutet maps out how different DNA-binding proteins in human cells react to certain biochemical modifications of the DNA molecule. The scientists report that some 'master' regulatory ...

Finding the proteins that unpack DNA

A new method allows researchers to systematically identify specialized proteins that unpack DNA inside the nucleus of a cell, making the usually dense DNA more accessible for gene expression and other functions. The method, ...

The TALE of new tools to study gene regulation

In nearly every organism's genome, scattered between genes that encode proteins, long regulatory regions stretch across expanses of DNA. Understanding what role these so-called enhancer regions play in controlling the activation ...

How cells protect themselves from mitochondrial defects

Cells need powerhouses known as mitochondria to utilize the energy stored in our food. Most of the proteins required for this powerhouse function are encoded in the nucleus and transported into the mitochondria after they ...

page 2 from 10