Cilia-free stem cells offer new path to study rare diseases

A group of rare diseases called "ciliopathies"—polycystic kidney disease notable among them—emerge from defects in cilia, the tiny hair-like structures on the surface of almost every cell type. But the specific molecular-level ...

Mapping how cell types and tissues develop

Researchers have developed a technique that allows them to look simultaneously at a spatial level and at a genome-wide level at epigenetic mechanisms underlying tissue development, a breakthrough with multiple scientific ...

Building a human body through gastrulation

A collaboration of researchers from Japan, Spain and the U.S. offers a phylogenetic and ontogenetic overview of the primitive streak and its role in mediating amniote (vertebrate animals that develop on land) gastrulation, ...

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