Macrocyclic peptides are promising candidates for pharmaceuticals, but their screening is difficult. Scientists have now developed an easy-to-use, high-throughput screening assay for cyclic peptides with affinity to ubiquitin, ...
Biochemistry
Feb 22, 2021
0
13
CRISPR deletion (CRISPR-del) is a new genome editing tool that can delete or cut out certain pieces of DNA in living cells with surgical precision. This allows researchers to study the functions of the diverse and poorly ...
Biotechnology
Feb 18, 2021
0
137
Researchers from Boston University School of Medicine (BUSM) provide a new genomics resource that details the small RNA transcriptomes (gene expression) of four bio-medically important mosquito species.
Cell & Microbiology
Jan 13, 2021
0
3
The past several decades have been hard on Apis mellifera, the Western honey bee. Originally native to Europe, Africa, and the Middle East, Western honey bees have spread worldwide thanks to the nutritional and medicinal ...
Plants & Animals
Dec 8, 2020
0
209
Researchers working on the Seeds of Discovery (SeeD) initiative, which aims to facilitate the effective use of genetic diversity of maize and wheat, have genetically characterized 79,191 samples of wheat from the germplasm ...
Plants & Animals
Sep 11, 2020
1
171
Gut microbes affect human health, but there is still much to learn, in part because they're not easy to collect. But researchers now report in ACS Nano that they have developed an ingestible capsule that in rat studies captured ...
Bio & Medicine
Sep 9, 2020
0
33
As new infectious diseases emerge and spread, one of the best shots against novel pathogens is finding new medicines or vaccines. But before drugs can be used as potential cures, they have to be painstakingly screened for ...
Analytical Chemistry
Aug 28, 2020
0
89
Fourier ptychographic microscopy (FPM) is a computational imaging and quantitative phase imaging (QPI) technique. It effectively tackles the trade-off between resolution and field-of-view (FOV) in conventional microscopy. ...
Optics & Photonics
Aug 24, 2020
0
44
Developing catalysts for sustainable fuel and chemical production requires a kind of Goldilocks Effect—some catalysts are too ineffective while others are too uneconomical. Catalyst testing also takes a lot of time and ...
Materials Science
Aug 5, 2020
1
138
Ketones are of great importance as building blocks in synthetic organic chemistry and biocatalysis. Most ketones cannot easily be quantitatively assayed due to the lack of visible photometric properties. Effective high-throughput ...
Biochemistry
Jul 9, 2020
0
88
