Nanochannel electroporation: Researchers do precise gene therapy without a needle
For the first time, researchers have found a way to inject a precise dose of a gene therapy agent directly into a single living cell without a needle.
For the first time, researchers have found a way to inject a precise dose of a gene therapy agent directly into a single living cell without a needle.
Bio & Medicine
Oct 16, 2011
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Just like a doctor adjusts the dose of a medication to the patient's needs, the expression of therapeutic genes, those modified in a person to treat or cure a disease via gene therapy, also needs to be maintained within a ...
Biotechnology
Jan 2, 2024
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The nonviral, bioinspired gene delivery method developed by researchers at RMIT University has proven effective in laboratory tests and is safer than standard viral approaches.
Bio & Medicine
Sep 24, 2019
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A research team led by Dr. Xiang David Li from the Department of Chemistry at The University of Hong Kong (HKU), in collaboration with scientists from Tsinghua University in China, the Rockefeller University, and the University ...
Biochemistry
Nov 7, 2018
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Delivering functional genes into cells to replace mutated genes, an approach known as gene therapy, holds potential for treating many types of diseases. The earliest efforts to deliver genes to diseased cells focused on DNA, ...
Biochemistry
Oct 16, 2018
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To predict the effects of a compound on the human body, researchers assess its biological activity, which requires pinpointing the affected biological processes within cells. Considering that living cells comprise many biological ...
Biotechnology
Sep 27, 2018
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There are about 20,000 genes in the human genome, but not all are used in all cells at all times. At any given moment, a cell is converting only roughly half its genes into proteins. And of those active genes, about 75 percent ...
Cell & Microbiology
Dec 10, 2015
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Quick changes in behavior – in worms, at least – can be triggered by a unique form of the molecule RNA acting within the nucleus of a cell, UC San Francisco researchers have discovered.
Cell & Microbiology
Aug 30, 2013
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A trio of groundbreaking publications from researchers in Northwestern University's Physical Sciences-Oncology Center (PS-OC) report important methodological advances that will enable a better understanding of how gene expression ...
Biotechnology
Aug 1, 2012
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With their potential to treat a wide range of diseases and uncover fundamental processes that lead to those diseases, embryonic stem (ES) cells hold great promise for biomedical science. A number of hurdles, both scientific ...
Cell & Microbiology
Jun 13, 2012
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