Research led by the University of Pennsylvania, Philadelphia, has used siRNA-based silencing of protein cyclophilin A (CyPA) to reduce tumor burden and extend the lives of patients with multiple myeloma.
University of Wisconsin–Madison researchers have developed a safer and more efficient way to deliver a promising new method for treating cancer and liver disorders and for vaccination—including a COVID-19 vaccine from ...
Biotechnology
Jul 2, 2020
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284
Therapeutic proteins are protein-based drug candidates bioengineered in the lab for pharmaceutical and clinical applications. Based on their pharmacokinetics, the candidates can be divided into groups that (1) replace a defective ...
(Phys.org) —Chemists from North Carolina State University have performed a DNA-based logic-gate operation within a human cell. The research may pave the way to more complicated computations in live cells, as well as new ...
Biochemistry
Jul 10, 2013
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0
Biologists at UC San Diego have succeeded in genetically engineering algae to produce a complex and expensive human therapeutic drug used to treat cancer.
Cell & Microbiology
Dec 10, 2012
1
0
(Phys.org)—A new US study has found a way of enabling larger nanoparticles than previously to penetrate brain tissues, which may provide a new means of delivering therapeutic drugs to brain tissues for targeted treatment ...
For the first time, researchers have found a way to inject a precise dose of a gene therapy agent directly into a single living cell without a needle.
Bio & Medicine
Oct 16, 2011
1
1
Using chemical "nanoblasts" that punch tiny holes in the protective membranes of cells, researchers have demonstrated a new technique for getting therapeutic small molecules, proteins and DNA directly into living cells.
Bio & Medicine
Jul 27, 2010
0
0
Several types of conventional cancer therapies, such as radiotherapy or chemotherapy, destroy healthy cells along with cancer cells. In advanced stages of cancer, tissue loss from treatments can be substantial and even fatal. ...
Bio & Medicine
Apr 22, 2024
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51
Mutations that disrupt development of germ cells cause infertility or birth defects. Mutations that cause female infertility in humans, such as mutations in the gene BMP15, also cause infertility in zebrafish. However, female ...
Cell & Microbiology
Jan 22, 2024
0
45
