New technique can track drug and gene delivery to cells
With targeted drug and gene therapies, finding the target cells is only half the battle. Once these agents reach a cell's surface, they still have to get inside and do their job.
With targeted drug and gene therapies, finding the target cells is only half the battle. Once these agents reach a cell's surface, they still have to get inside and do their job.
Bio & Medicine
May 22, 2018
0
21
MIT engineers have designed magnetic protein nanoparticles that can be used to track cells or to monitor interactions within cells. The particles, described today in Nature Communications, are an enhanced version of a naturally ...
Bio & Medicine
Nov 2, 2015
0
50
Acne, a scourge of adolescence, may be about to meet its ultra high-tech match. By using a combination of ultrasound, gold-covered particles and lasers, researchers from UC Santa Barbara and the private medical device company ...
Bio & Medicine
Mar 19, 2015
0
143
Stem cells hold great promise as a means of repairing cells in conditions such as multiple sclerosis, stroke or injuries of the spinal cord because they have the ability to develop into almost any cell type. Now, new research ...
Cell & Microbiology
Sep 18, 2014
0
0
Rice University researchers are making strides toward a set of rules to custom-design Lego-like viral capsid proteins for gene therapy.
Biotechnology
Aug 12, 2013
0
0
Researchers from Johns Hopkins and Northwestern universities have discovered how to control the shape of nanoparticles that move DNA through the body and have shown that the shapes of these carriers may make a big difference ...
Bio & Medicine
Oct 12, 2012
0
0
The targeted treatment of pan-cancer by messenger RNA (mRNA) vaccine is a hot topic in drug research. A key challenge in mRNA design is the construction of delivery systems called lipid nanoparticles (LNPs), which serve as ...
Bio & Medicine
Jun 12, 2024
0
0
The Hirohide Saito Laboratory has developed cyclic RNA switches that can control gene expression in a cell type-specific manner using miRNAs and RNA-binding proteins and has successfully constructed an artificial gene circuit ...
Cell & Microbiology
Feb 16, 2023
0
2
Biofidelity, a genomic technology company, has developed a low-cost, simple and rapid assay for single-molecule detection of multiple gene fusions from RNA. A new scientific paper describes the assay and how detecting these ...
Biotechnology
Oct 19, 2022
0
8
Parkinson's disease, Huntington's disease, cystic fibrosis and many other fatal human diseases are hereditary. Many cancers and cardiovascular diseases are also caused by genetic defects. Gene therapy is a promising possibility ...
Cell & Microbiology
Feb 16, 2018
0
20