Related topics: mice · cancer · protein · united states

Weaker transcription factors are better when they work together

Bioengineers can tailor the genomes of cells to create "cellular therapies" that fight disease, but they have found it difficult to design specialized activating proteins called transcription factors that can throw the switch ...

Deep learning for new protein design

The key to understanding proteins—such as those that govern cancer, COVID-19, and other diseases—is quite simple: Identify their chemical structure and find which other proteins can bind to them. But there's a catch.

Novel targets identified for treatment of schistosomiasis

The worms that cause schistosomiasis (Schistosoma mansoni) are unusual in several ways, especially the fact that male and female adults must stay paired together throughout their lives for reproduction to be successful. Females ...

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