'Directing' evolution to identify potential drugs earlier in discovery
Scientists have developed a technique that could significantly reduce the time of discovering potential new antibody-based drugs to treat disease.
Scientists have developed a technique that could significantly reduce the time of discovering potential new antibody-based drugs to treat disease.
Biotechnology
Apr 14, 2020
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167
When attacked by pathogenic microbes, plants protect themselves by deploying numerous secondary metabolites inhibitory to the pathogen. These metabolites are thought to nonspecifically inhibit both pathogenic and beneficial ...
Biotechnology
Apr 9, 2020
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5
A new multinational study has shown how the process of distinguishing viruses and bacteria could be accelerated through the use of computational methods.
Biotechnology
Mar 31, 2020
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250
Antibodies are proteins that act as recognition molecules for pathogens, like viruses and bacteria, and are the workhorses of the body's immune system. They recognize specific molecules and bind to them very strongly, which ...
Bio & Medicine
Mar 23, 2020
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300
CRISPR-based genetic screens have helped scientists identify genes that are key players in sickle-cell anemia, cancer immunotherapy, lung cancer metastasis, and many other diseases. However, these genetic screens are limited ...
Biotechnology
Mar 16, 2020
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2615
After the summer's devastating bushfires, the New South Wales government announced a plan to airdrop one million poisoned baits in the state's most vulnerable regions over the next year. The plan is aimed at protecting surviving ...
Plants & Animals
Mar 13, 2020
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24
CeMM Researchers have studied how solute carriers (SLCs), a large family of membrane transport proteins, influence the activity and potency of cytotoxic drugs. Their study in Nature Chemical Biology uncovers the dependency ...
Biochemistry
Mar 10, 2020
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108
Researchers at Princeton University have revealed the inner workings of a gene repression mechanism in fruit fly embryos, adding insight to the study of human diseases.
Cell & Microbiology
Mar 6, 2020
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172
Mitochondria cannot autonomously cope with stress and must instead call on the cell for help. Molecular geneticists at LMU have identified the long-sought signaling pathway which enables the organelles to do so.
Cell & Microbiology
Mar 5, 2020
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156
New York University biologists captured highly transient interactions between transcription factors—proteins that control gene expression—and target genes in the genome and showed that these typically missed interactions ...
Molecular & Computational biology
Mar 2, 2020
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40