Artificial intelligence can predict on- and off-target activity of CRISPR tools that target RNA instead of DNA, according to new research published in Nature Biotechnology.
Biotechnology
Jul 3, 2023
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4643
While the presence of harmful critters in your home may be addressed by a call to the exterminator, harmful parasites in the body can be much harder to expel. A single-celled parasite known as Toxoplasma gondii (hereafter ...
Cell & Microbiology
Jun 6, 2023
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19
A review of gene editing techniques suggests that the CRISPR/Cas (clustered regularly interspaced short palindromic repeats/Cas) method could be a possible "savior" for rice crops threatened by climate change and high food ...
Biotechnology
Mar 3, 2023
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8
New research led by bioengineers at the University of California San Diego could make it much simpler to repair disease-causing mutations in RNA without compromising precision or efficiency.
Biotechnology
Feb 10, 2022
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119
A team of researchers working at the University of Münster has found a high frequency of unwanted duplications during routine CRISPR-Cas9 genetic insertions in mice. In their paper published in the journal Science Advances, ...
CRISPR-based gene editing has potential therapeutic benefits but also some technical shortcomings. One set of these gene editing tools, base editors, can rewrite the four individual DNA letters, or bases— A, C, T or G—which ...
Biotechnology
Feb 11, 2020
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26
Distortions to DNA, which occur routinely during gene expression and other cellular processes, could lead to off-target changes to the genome when using CRISPR-Cas9, a new study suggests. The Medical Research Council scientists ...
Biotechnology
Feb 26, 2019
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28
An international team of researchers has developed a way to detect the likelihood of making off-target cuts when using the CRISPR-Cas9 gene editing technique. In their paper published in the journal Nature, the group describes ...
Scientists in the US have released a paper showing that they have successfully edited human embryos to correct a mutation that causes an inheritable heart condition. The findings are hugely important as they demonstrate for ...
Biotechnology
Aug 3, 2017
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28
Harvard Medical School and Cornell University scientists have generated near-atomic resolution snapshots of CRISPR that reveal key steps in its mechanism of action. The findings, published in Cell on June 29, provide the ...
Biotechnology
Jun 29, 2017
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