Super-resolution microscopy reveals fine detail of cellular mesh

One of today's sharpest imaging tools, super-resolution microscopy, produces sparkling images of what until now has been the blurry interior of cells, detailing not only the cell's internal organs and skeleton, but also providing ...

Visualizing single molecules in whole cells with a new spin

Cell biologists traditionally use fluorescent dyes to label and visualize cells and the molecules within them under a microscope. With different super-resolution microscopy methods, they can even light up single molecules ...

'Volumetric' imaging method reveals chemical content

A "chemical imaging" system that uses a special type of laser beam to penetrate deep into tissue might lead to technologies that eliminate the need to draw blood for analyses including drug testing and early detection of ...

Enhancing molecular imaging with light

In 2014, an international trio won the Nobel Prize in Chemistry for developing super-resolution fluorescence microscopy, a technique that made it possible to study molecular processes in living cells.

qPAINT counts biomolecules inside cells

Many biological and pathological processes are not strictly controlled by the presence, absence or function of biomolecules such as proteins or nucleic acids but rather by subtle changes in their numbers at specific locations ...

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