Cas3: a biological fishing rod and a shredder rolled into one

CRISPR-Cas9 has made gene editing a lot easier, and will eventually contribute to elimination of hereditary diseases from our DNA. But despite the fact that researchers use CRISPR-Cas9 and similar bacterial immune systems ...

How a shape-shifting DNA-repair machine fights cancer

(Phys.org) —Maybe you've seen the movies or played with toy Transformers, those shape-shifting machines that morph in response to whatever challenge they face. It turns out that DNA-repair machines in your cells use a similar ...

NUS researchers identify a novel double-stranded DNA structure

By way of mechanical stretching, National University of Singapore researchers identify a novel double-stranded DNA structure, thus successfully resolving a 16-year-old scientific debate over the existence of a double-stranded ...

Math shows how DNA twists, turns and unzips

If you've ever seen a picture of a DNA molecule, you probably saw it in its famous B-form: two strands coiling around each other in a right-handed fashion to form a double helix. But did you know that DNA can change its shape?

Understanding DNA Repair and Cancer

(PhysOrg.com) -- A protein that plays a key role in copying DNA also plays a vital role in repairing breaks in it, UC Davis scientists have found. The work is helping researchers understand how cancer cells can resist radiation ...

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