A unique approach for studying changes in chemical markers on DNA

A new method to study specific changes in DNA after replication has been published as a technical report in Nature Cell Biology. Researchers developed a highly sensitive, quantitative mass spectrometry-based approach, called ...

DNA repair scheme gets closer look for cancer therapy

Researchers from Rice University and St. Jude Children's Research Hospital in Memphis, Tennessee, Have taken a close look at one of the ways cells repair broken strands of DNA and discovered details that could help make a ...

CRISPR insight: How to fine-tune Cas protein's grip on DNA

At the heart of every CRISPR reaction, whether naturally occurring in bacteria or harnessed by CRIPSR-Cas gene editing technology, is a strong molecular bond of a Cas protein via a guide RNA to its target site on DNA. It's ...

Even good gene edits can go bad

A Rice University lab is leading the effort to reveal potential threats to the efficacy and safety of therapies based on CRISPR-Cas9, the Nobel Prize-winning gene editing technique, even when it appears to be working as planned.

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