Study reveals DNA 'grammar'

DNA three-dimensional structure is determined by a series of spatial rules based on particular protein sequences and their order. This was the finding of a study recently published in Genome Biology by Luca Nanni, Ph.D. student ...

Droplets are key to cells' dynamic activities

A cell is a complex machine whose flexible architecture enables it to take part in life's activities: relaying information, managing waste, responding to stress.

How cellular machinery labels proteins for degradation

Proteins are molecular work horses in the cell that perform specific tasks, but it is essential that the timing of protein activities is exquisitely controlled. When proteins have fulfilled their tasks, their degradation ...

Lighting up proteins with Immuno-SABER

To better understand how tissues and organs develop, fail to function, and regenerate over time, researchers would like to visualize their constituent cells' repertoires of molecules within 3-D space. Ambitious efforts like ...

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