Fighting sleeping sickness with X-ray lasers
Structure analysis of the trypanosomal protein Cathepsin B is among the scientific breakthroughs of 2012.
Structure analysis of the trypanosomal protein Cathepsin B is among the scientific breakthroughs of 2012.
Biochemistry
Dec 21, 2012
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Manipulation of male and/or female genitalia results in a suite of changes in female reproductive behavior in tsetse flies, carriers of African sleeping sickness.
Plants & Animals
May 14, 2009
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Infectious African sleeping sickness is widespread south of the Sahara Desert. Although the around sixty million people residing in tropical Africa run the risk of becoming infected every day, only around four million of ...
Biochemistry
Dec 14, 2012
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An international team of scientists has for the first time crystallised a key enzyme of the pathogen for African sleeping sickness in a living cell and investigated it with the worlds strongest X-ray laser. This new ...
Biochemistry
Jan 30, 2012
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(PhysOrg.com) -- The causative agent of African sleeping sickness, annually responsible for several thousands of deaths in Africa and South America, is a motile cell: it propels itself through its hosts bloodstream ...
Cell & Microbiology
Jun 21, 2011
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Trypanosoma brucei, the parasite that causes sleeping sickness, is transmitted to mammals by the tsetse fly, and must adapt to the divergent metabolisms of its hosts. A new study shows how it copes with the frugal diet offered ...
Cell & Microbiology
Jul 8, 2013
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In the Atlantic Forest of Brazil, leaf-cutter ants carry fresh foliage back to their home colony. There, the partially digested leaves nourish a "garden" of white fungus that the ants cultivate to feed their larvae, their ...
Plants & Animals
Aug 5, 2014
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Sleeping sickness, caused by the trypanosome Trypanosoma brucei, is transmitted to humans (and animals) via the bite of the tsetse fly. New research published in BioMed Central's open access journal Microbial Cell Factories ...
Cell & Microbiology
Feb 14, 2012
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Scientists at the University of Oulu, Finland, and at the Helmholtz Center Berlin (HZB) have shown the way to new directions in drug development against African sleeping sickness and other tropical parasitic infections. This ...
Biochemistry
Nov 7, 2013
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Caught in the act! Researchers from the University of Bristol have observed mating for the first time in the microbes responsible for African sleeping sickness. This tropical disease is caused by trypanosomes, single-celled ...
Cell & Microbiology
Jan 3, 2014
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