Shining a light on gene regulation

Cancer treatments—from radiation to surgery to chemotherapy—are designed to remove or kill cancerous cells, but healthy cells often become collateral damage in the process. What if you could use lasers to pinpoint the ...

Novel nanoparticle delivers powerful RNA interference drugs

Silencing genes that have malfunctioned is an important approach for treating diseases such as cancer and heart disease. One effective approach is to deliver drugs made from small molecules of ribonucleic acid, or RNA, which ...

Image-guided breast cancer therapy enabled by nanodrug

By combining an iron oxide nanoparticle, a tumor-targeting peptide, and a therapeutic nucleic acid into one construct, a team of investigators from the Massachusetts General Hospital and Harvard Medical School have created ...

Understanding how cells respond to nanoparticles

Gold nanoparticles are showing real promise as vehicles for efficiently delivering therapeutic nucleic acids, such as disease-fighting genes and small interfering RNA (siRNA) molecules, to tumors. Now, a team of investigators ...

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