It is now possible to deliver therapeutics based on short interfering RNAs to hepatocytes; however, new delivery solutions are necessary to target additional organs. In a new report now published in Nature Biotechnology, ...
Scientists from the University of Cambridge have developed a platform that uses nanoparticles known as metal-organic frameworks to deliver a promising anti-cancer agent to cells.
Bio & Medicine
Sep 16, 2019
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494
Inspired by tiny particles that carry cholesterol through the body, MIT chemical engineers have designed nanoparticles that can deliver snippets of genetic material that turn off disease-causing genes.
Bio & Medicine
Feb 11, 2014
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0
Small interfering RNAs (siRNAs) are novel therapeutics that can be used to treat a wide range of diseases. This has led to a growing demand for selective, efficient, and safe ways of delivering siRNA in cells. Now, in a cooperation ...
Bio & Medicine
Apr 19, 2023
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47
Small interfering RNAs—or siRNAs—hold promise to treat tumors, through their ability to specifically knock down oncogenes that promote tumor growth without the toxicity that accompanies chemotherapy. However, the siRNAs ...
Bio & Medicine
May 24, 2022
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128
Charcot-Marie Tooth disease is the most common hereditary neurological disease in the world. It affects the peripheral nerves and causes progressive paralysis of the legs and hands. No treatment is currently available to ...
Biotechnology
Mar 9, 2021
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109
In most organisms, small bits of RNA play a key role in gene regulation by silencing gene expression. They do this by targeting and docking onto complementary sequences of gene transcripts (also RNA molecules), which stop ...
Plants & Animals
Jul 28, 2020
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127
With RNA being the core carrier of genetic information in life, understanding how RNA and small interfering RNA (siRNA) transmits responses to external stress may be better understood following new research led by Southern ...
Plants & Animals
Apr 30, 2020
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18
Drugs that help prevent the formation of unwanted or harmful proteins are currently being developed to treat a number of diseases, including cancer. The drugs are based on small interfering RNA, or siRNA, which are pieces ...
Materials Science
Aug 28, 2019
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50
In a recent study in mice, researchers found a way to deliver specific drugs to parts of the body that are exceptionally difficult to access. Their Y-shaped block catiomer (YBC) binds with certain therapeutic materials forming ...
Bio & Medicine
Apr 24, 2019
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