Using nanoparticles, Yale researchers have developed a drug-delivery system that could reduce organ transplant complications by hiding the donated tissue from the recipient's immune system.
Bio & Medicine
Aug 4, 2017
0
57
Drugs that help prevent the formation of unwanted or harmful proteins are currently being developed to treat a number of diseases, including cancer. The drugs are based on small interfering RNA, or siRNA, which are pieces ...
Materials Science
Aug 28, 2019
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50
With RNA being the core carrier of genetic information in life, understanding how RNA and small interfering RNA (siRNA) transmits responses to external stress may be better understood following new research led by Southern ...
Plants & Animals
Apr 30, 2020
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18
For millions of people hearing disorders make a negative impact on their lives. Scientists are looking into new ways of treating hearing disorders, by using different sorts of nanoparticles as original inner ear delivery ...
Bio & Medicine
Jun 13, 2011
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0
Drinking green tea has been linked to health benefits ranging from cardiovascular disease prevention to weight loss. Although many of these claims still need to be verified in the clinic, an antioxidant in green tea called ...
Biochemistry
Sep 19, 2018
0
13
Small interfering RNAs (siRNAs) are novel therapeutics that can be used to treat a wide range of diseases. This has led to a growing demand for selective, efficient, and safe ways of delivering siRNA in cells. Now, in a cooperation ...
Bio & Medicine
Apr 19, 2023
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47
In most organisms, small bits of RNA play a key role in gene regulation by silencing gene expression. They do this by targeting and docking onto complementary sequences of gene transcripts (also RNA molecules), which stop ...
Plants & Animals
Jul 28, 2020
0
127
RNA interference is a gene regulatory mechanism in which the expression of specific genes is downregulated by endogenous microRNAs or by small interfering RNAs (siRNAs). Although siRNAs have broad potential for gene-silencing ...
Molecular & Computational biology
Oct 16, 2020
0
3
In a study published in the Clinical and Translational Medicine, a Nanjing University research group evaluated the on- and off-target effects of self-assembled siRNA delivery system.
Bio & Medicine
Feb 7, 2024
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0
Viruses attack the body by sending their genetic code—DNA and RNA—into cells and multiplying. A promising class of therapeutics that uses synthetic nucleic acids to target and shut down specific, harmful genes and prevent ...
Molecular & Computational biology
May 17, 2021
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