Geneticists exploring the dark heart of the human genome have discovered big chunks of Neanderthal and other ancient DNA. The results open new ways to study both how chromosomes behave during cell division and how they have ...
Evolution
Jun 18, 2019
0
938
A new study led by Imperial College London finds that drug-resistant mold is spreading from the environment and infecting susceptible people's lungs.
Cell & Microbiology
Apr 25, 2022
0
40
Was there a single migration event or gradual mixing of cultures that gave rise to modern Japanese?
Archaeology
Mar 11, 2015
4
70
Take a wild, common forest-dwelling mouse-like rodent, known as a vole, and subject it to 13 rounds of selection for increased aerobic exercise metabolism, and what do you get? A mighty "mouse" with a 48 percent higher peak ...
Evolution
Mar 5, 2015
0
7
Within the salty lakes of the Bahama's San Salvador Island is an amazing diversity of fishes that may rival Charles Darwin's finches in the Galapagos.
Evolution
Dec 27, 2016
0
156
Optothermal nanotweezers are an innovative optical design method that has revolutionized classical optical techniques to capture a broad range of nanoparticles. While the optothermal temperature field can be employed for ...
Nearly 10,000 years ago, humans settling in the Fertile Crescent, the areas of the Middle East surrounding the Tigris and Euphrates rivers, made the first switch from hunter-gatherers to farmers. They developed close bonds ...
Evolution
Dec 5, 2022
0
222
I've often wondered what happens between the time an egg is fertilized and the time the ball of cells that it becomes nestles into the uterine lining. It's a period that we know very little about, a black box of developmental ...
Medical research
May 27, 2016
1
6
In the version of evolutionary theory most of us are familiar with, randomly occurring variation in traits, caused by mutations in our DNA, can be fixed in a population through natural selection. However, writing in Epigenetics ...
Evolution
Sep 10, 2019
0
325
Atlantic salmon production could be boosted by a new technology that will help select the best fish for breeding.
Ecology
Feb 13, 2014
0
0
A single-nucleotide polymorphism (SNP, pronounced snip) is a DNA sequence variation occurring when a single nucleotide — A, T, C, or G — in the genome (or other shared sequence) differs between members of a species (or between paired chromosomes in an individual). For example, two sequenced DNA fragments from different individuals, AAGCCTA to AAGCTTA, contain a difference in a single nucleotide. In this case we say that there are two alleles : C and T. Almost all common SNPs have only two alleles.
Within a population, SNPs can be assigned a minor allele frequency — the lowest allele frequency at a locus that is observed in a particular population. This is simply the lesser of the two allele frequencies for single-nucleotide polymorphisms[1]. There are variations between human populations, so a SNP allele that is common in one geographical or ethnic group may be much rarer in another.
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