Mini but mighty: Tiny WNT messengers help muscles grow

WNT signaling is crucial for the development of organisms and the maintenance of tissue homeostasis, since the WNT messengers are involved in a variety of cellular functions. In skeletal muscle, for example, they can increase ...

Individual cells respond to electrical signal

Researchers at the Department of Molecular Nanofabrication (part of the University of Twente's MESA+ Institute for Nanotechnology) have published their preliminary results in a prominent article in Angewandte Chemie. This ...

Signaling molecule crucial to stem cell reprogramming

While investigating a rare genetic disorder, researchers at the University of California, San Diego School of Medicine have discovered that a ubiquitous signaling molecule is crucial to cellular reprogramming, a finding with ...

What makes stem cells tick?

Investigators at the Burnham Institute for Medical Research (Burnham) and The Scripps Research Institute (TSRI) have made the first comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) ...

Structural data reveals new mechanism behind protein transport

In order for newly-produced secretory or membrane proteins to find their final destination, the proteins have signal-sequences connected to themselves as a form of address tag. Furthermore, they use a particle guiding them ...

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