Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form a node known as the transcription ...
Biotechnology
Jul 3, 2024
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49
We combined a machine learning algorithm with knowledge gleaned from hundreds of biological experiments to develop a technique that allows biomedical researchers to figure out the functions of the proteins that turn genes ...
Cell & Microbiology
Aug 9, 2021
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22
Genome sequencing alone provides researchers with only limited information on the organism works because it neither reveals how the system is regulated nor does it indicate the role of each specific DNA sequence or RNA transcript. ...
Biotechnology
Mar 26, 2012
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0
Histones—proteins that package DNA—affect cell function differently than previously assumed: the cell doesn't need the histone H3.3 to read genes. Molecular biologists from the University of Zurich demonstrate that fruit ...
Cell & Microbiology
Nov 13, 2012
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0
In a joint collaboration, Danish and German researchers have characterized a cellular activity that protects our cells from potentially toxic by-products of gene expression. This activity is central for the ability of multicellular ...
Molecular & Computational biology
Jan 5, 2021
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85
Northwestern Medicine investigators have discovered novel mechanisms underlying a specific transcription factor essential for elongation control, the process of synthesizing RNA from DNA, according to findings published in ...
Cell & Microbiology
Aug 11, 2022
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13
Gao Caixia's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences (CAS) has developed a new method of downregulating gene translation to a predictable and desired level in plants ...
Biotechnology
Mar 9, 2023
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9
Although many people are aware that chromosomal damage and shortening contribute to the aging process, understanding how chromosomal defects occur is about more than just finding a way to turn back the clock. Large changes ...
Cell & Microbiology
Jan 24, 2019
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5
The central dogma of molecular biology describes the flow of genetic information. It was first described by Francis Crick in 1956 as one-way traffic: as: "DNA makes RNA and RNA makes protein."
Cell & Microbiology
Mar 11, 2015
2
28
Researchers in Japan have discovered that the DNA inside human cells moves around less when its genes are active. The study, which will be published March 1 in the Journal of Cell Biology, suggests that RNA polymerase II ...
Cell & Microbiology
Mar 1, 2019
0
15
