Life is complicated enough, so you can forgive the pioneers of DNA biology for glossing over transcriptional elongation control by RNA polymerase II, the quick and seemingly bulletproof penultimate step in the process that ...
Cell & Microbiology
Dec 22, 2011
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Just like orchestra musicians waiting for their cue, RNA polymerase II molecules are poised at the start site of many developmentally controlled genes, waiting for the "Go!"- signal to read their part of the genomic symphony. ...
Cell & Microbiology
Jul 14, 2011
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Researchers at Albert Einstein College of Medicine of Yeshiva University have for the first time observed the activity of a single gene in living cells. In an unprecedented study, published in the April 22 online edition ...
Biotechnology
Apr 21, 2011
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A paper published by Cell Press in the April 8th issue of the journal Cell Stem Cell reveals a new and more efficient method for reprogramming adult mouse and human cells into an embryonic stem cell-like state and could lead ...
Cell & Microbiology
Apr 7, 2011
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When most genes are transcribed, the nascent RNAs they produce are not quite ready to be translated into proteins - they have to be processed first. One of those processes is called splicing, a mechanism by which non-coding ...
Cell & Microbiology
Oct 25, 2010
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In all organisms, RNA synthesis is carried out by proteins - known as RNA polymerases (RNAPs) - that transcribe the genetic information from DNA in a highly-regulated, multi-stage process. RNAP is the key enzyme involved ...
Biotechnology
Jul 15, 2010
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Gene expression takes place in two stages: the transcription of DNA to RNA by an enzyme called RNA polymerase, followed by the translation of this RNA into proteins, whose behaviour affects the characteristics of each individual.
Biochemistry
Jun 17, 2010
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DNA replication, the process by which a strand of DNA is copied during cell proliferation , and DNA transcription, the process by which the message in the DNA is translated into messenger RNA, involve the same "track" or ...
Cell & Microbiology
May 13, 2010
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New evidence in embryonic stem cells shows that mammalian genes may all have a layer of control that acts essentially like the pause button on your DVR. The researchers say the results show that the pausing phenomenon, previously ...
Biotechnology
Apr 29, 2010
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Researchers from NYU Langone Medical Center have discovered and characterized a general mechanism that controls transcription elongation in bacteria. The mechanism, described in the April 23 issue of Science, relies on physical ...
Biotechnology
Apr 22, 2010
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