Most people are familiar with the cell nucleus from grade school biology as a storage compartment for DNA. But the nucleus also contains several distinct structures, called nuclear bodies or domains, whose roles scientists ...
Molecular & Computational biology
Mar 2, 2022
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89
The basic process of life, known as transcription, is the process by which the genetic information stored in DNA is copied by specific enzymes called RNA polymerases into RNA molecules. Despite a huge progress in our understanding ...
Molecular & Computational biology
Feb 21, 2022
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39
University of Toronto researchers have created a first-in-class functional catalog of proteins that activate gene expression, with implications for tailored therapy for cancer and other diseases that occur when wrong genes ...
Molecular & Computational biology
Feb 9, 2022
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92
A team of physicists working at the intersection of theory and experiment are shedding new light on the "teamwork" of molecular motors—called RNA polymerases (RNAPs)—that mediate DNA transcription. During transcription, ...
General Physics
Dec 9, 2021
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35
Bacteria need to constantly adapt to compete against other species for nutrient sources and to survive against threats such as antibiotics and toxins.
Cell & Microbiology
Nov 16, 2021
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33
Northwestern Medicine scientists have identified a critical checkpoint in transcription elongation, the process of synthesizing RNA from a DNA template, according to findings published in Molecular Cell.
Molecular & Computational biology
Sep 6, 2021
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99
We combined a machine learning algorithm with knowledge gleaned from hundreds of biological experiments to develop a technique that allows biomedical researchers to figure out the functions of the proteins that turn genes ...
Cell & Microbiology
Aug 9, 2021
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22
The corona pandemic has ensured that the term "mRNA" is now also known to a large public beyond laboratories and lecture halls. However, the molecule is much more than an important component of a successful vaccine against ...
Molecular & Computational biology
Jul 14, 2021
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8
On scales too small for our eyes to see, the business of life happens through the making of proteins, which impart to our cells both structure and function. Cellular proteins get their marching orders from genetic instructions ...
Cell & Microbiology
May 27, 2021
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10
A bacterial protein helps to stop transcription—the process of making RNA copies of DNA to carry out the functions of the cell—by causing the cellular machinery that transcribes the DNA to pause at the appropriate spots ...
Biotechnology
May 7, 2021
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