The research team of the Center for RNA Research at IBS has succeeded in revealing that the dsRNAs and Protein Kinase R (PKR) regulate division of mammalian cells.
Cell & Microbiology
Dec 2, 2014
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Genetic information encoded in genomic DNA is transcribed to mRNAs and then the codons on mRNA are decoded by transfer RNAs (tRNAs) during protein synthesis. tRNAs deliver amino acids to ribosomes and proteins are synthesized ...
Biochemistry
Dec 27, 2022
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68
Trypanosomatids are single-cell parasites that cause major diseases, such as sleeping sickness and Rose of Jericho, which affect millions of people. Trypanosoma parasites are transmitted to mammals by the blood-sucking tsetse ...
Cell & Microbiology
Mar 17, 2021
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43
Viruses can be elusive quarry. RNA viruses are particularly adept at defeating antiviral drugs because they are so inaccurate in making copies of themselves. With at least one error in every genome they copy, viral genomes ...
Cell & Microbiology
Nov 20, 2012
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How does the bacterium Shigella—the cause of a deadly diarrheal disease—detect that it's in a human host? Ohio University scientists have found that a biological "RNA thermometer" monitors whether the environment is right ...
Cell & Microbiology
May 21, 2013
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Protein synthesis is programmed by messenger RNAs, and when enough of a given protein has been made, the mRNAs that encode it are destroyed. LMU researchers have now shown that protein synthesis and mRNA degradation are structurally ...
Cell & Microbiology
Jan 26, 2017
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8
Ludwig Maximilian University of Munich researchers have elucidated a mechanism that recycles bacterial ribosomes stalled on messenger RNAs that lack termination codons. The protein involved provides a potential target for ...
Cell & Microbiology
Dec 5, 2016
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7
(Phys.org)—An interdisciplinary effort at the Friedrich Miescher Institute for Biomedical Research (FMI) addressed the question of how mRNA content, which is translated into proteins, is regulated in the cell. Supported ...
Cell & Microbiology
Sep 7, 2012
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Transcription is a cellular process by which genetic information from DNA is copied to messenger RNA for protein production. But anticancer drugs and environmental chemicals can sometimes interrupt this flow of genetic information ...
Biochemistry
Aug 21, 2012
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Circular RNAs were recently shown to be abundant in mice and humans where they influence gene expression.
Biochemistry
May 22, 2013
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