(PhysOrg.com) -- Scientists at the University of Manchester have identified an extra step in protein production, a major activity of all cells, which they believe impacts particularly on how our cells respond to stresses ...
Cell & Microbiology
May 21, 2010
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Mitochondria are compartments within cells and have their own DNA. The key protein required for the expression of the genetic information in this DNA is the mitochondrial RNA polymerase enzyme. Its three-dimensional structure ...
Cell & Microbiology
Sep 26, 2011
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(Phys.org)—Multiple RNA sequences can code for the same amino acid, but differences in their respective "optimality" slow or accelerate protein translation. Stanford biologists find optimal and non-optimal codons are consistently ...
Cell & Microbiology
Jan 31, 2013
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Improperly formed proteins can cause a host of serious illnesses, from muscular dystrophy to cystic fibrosis. A question of enormous import in research, beyond the challenge of determining how malformed proteins contribute ...
Biotechnology
Dec 14, 2015
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Gene transcription is central to cell function, as it converts the information stored in the DNA into RNA molecules of defined sequence, which then program protein synthesis. The enzyme RNA polymerase II (Pol II) is responsible ...
Cell & Microbiology
Feb 23, 2011
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At crucial points in the metabolism of all organisms, a protein with the unwieldy name of Translation Elongation Factor P (EF-P, for short) takes center stage. What it actually does during protein synthesis has only now been ...
Cell & Microbiology
Dec 14, 2012
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The zebrafish is an important model organism in biology. Humans and zebrafish share 70 percent of their genes, and more than 80 percent of human genes associated with disease are known to have a zebrafish counterpart. Additionally, ...
Molecular & Computational biology
Oct 8, 2019
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With five-year survival rates being around 30 percent for patients with distant metastatic disease, cutaneous melanoma is the leading cause of skin cancer-related deaths. The major causes of the low survival rate for melanoma ...
Cell & Microbiology
Oct 29, 2018
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By constructing a microscope apparatus that achieves resolution never before possible in living cells, researchers at Albert Einstein College of Medicine of Yeshiva University have illuminated the molecular interactions that ...
Cell & Microbiology
Sep 15, 2010
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Scientists at the Friedrich Miescher Institute for Biomedical Research have identified a novel and unexpected regulatory activity of RNA at the edge of inactive chromosomal regions. In their publication in Nature Structural ...
Cell & Microbiology
Aug 8, 2013
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