DNA is a molecular manual that contains instructions for building life. And, like any manual, DNA isn't all that useful if it remains unopened and unread. In order to transcribe DNA, the enzyme RNA polymerase, or RNAP, must ...
Molecular & Computational biology
Jan 10, 2019
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Genes contain all the information needed for the functioning of cells, tissues and organs. Gene expression, meaning when and how the genes are read and executed, is thoroughly regulated like an assembly line with several ...
Cell & Microbiology
Jan 9, 2019
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The death-cap mushroom has a long history as a tool of murder and suicide, going back to ancient Roman times. The fungus, Amanita phalloides, produces one of the world's deadliest toxins: α-amanitin. While it may seem ill-advised, ...
Materials Science
Apr 11, 2018
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Researchers at Umeå and Stockholm universities in Sweden and Johns Hopkins University School of Medicine in the U.S. have published a new study in the journal Molecular Cell. They show how the protein CBP affects the expression ...
Biotechnology
Oct 20, 2017
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Researchers propose "Oritatami" as a mathematical model of the cotranscriptional folding of RNA in order to widen applications of RNA origami—one of the most significant experimental breakthroughs in molecular self-assembly.
Cell & Microbiology
Jul 6, 2016
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RNA polymerase II (Pol II), a key enzyme in our gene expression, is responsible for transcribing DNA into messenger RNA. Errors in transcription can cause deleterious effect upon repeated translation of erroneous mRNA into ...
Cell & Microbiology
May 3, 2016
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Scientists at the Helmholtz Zentrum München, working with colleagues from the Ludwig-Maximilians-Universität München, have developed a method for the thorough analysis of protein modifications. They mapped the phosphorylation ...
Cell & Microbiology
Jan 21, 2016
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Nuclear pores in the nuclear membrane do not only control the transport of molecules into and out of the nucleus but also play an important role in gene expression. Researchers at the Max F. Perutz Laboratories (MFPL) of ...
Cell & Microbiology
Aug 28, 2015
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28
Every inch of our body, inside and out, is oozing with bacteria. In fact, the human body carries 10 times the number of bacterial cells as human cells. Many are our friends, helping us digest food and fight off infections, ...
Cell & Microbiology
May 7, 2015
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To understand how transposable elements shape genomes, where they are maintained over generations, it is vital to discover the mechanisms behind their targeted integration. Researchers from the Laboratoire Pathologie et Virologie ...
Biotechnology
May 5, 2015
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