In a new Nature Communications study, researchers have explored the construction of genetic circuits on single DNA molecules, demonstrating localized protein synthesis as a guiding principle for dissipative nanodevices, offering ...
An international team of scientists has recently developed a novel type of nano engine made of DNA. It is driven by a clever mechanism and can perform pulsing movements. The researchers are now planning to fit it with a coupling ...
Bio & Medicine
Oct 19, 2023
0
793
Modern medicine depends on antibiotics to treat infections by disabling targets inside bacterial cells. Once inside these cells, antibiotics bind to certain sites on specific enzyme targets to stop bacterial growth. Randomly ...
Cell & Microbiology
Aug 30, 2023
0
47
Cells contain machinery that duplicates DNA into a new set that goes into a newly formed cell. That same class of machines, called polymerases, also build RNA messages, which are like notes copied from the central DNA repository ...
Molecular & Computational biology
Jun 11, 2021
39
12351
New research has identified and described a cellular process that, despite what textbooks say, has remained elusive to scientists until now—precisely how the copying of genetic material that, once started, is properly turned ...
Cell & Microbiology
Nov 26, 2020
8
1789
On the evolutionary tree, humans diverged from yeast roughly 1 billion years ago. By comparison, two seemingly similar species of bacteria, Escherichia coli and Bacillus subtilis, have been evolving apart for roughly twice ...
Molecular & Computational biology
Sep 3, 2020
1
75
Researchers at the University of Toronto have shown that an enzyme called RNA polymerase (Pol) II drives generation of the building blocks of ribosomes, the molecular machines that manufacture all proteins in cells based ...
Molecular & Computational biology
Jul 15, 2020
0
309
The lifespans of flies and worms are prolonged by limiting the activity of an enzyme common to all animals, finds a UCL-led study.
Cell & Microbiology
Nov 29, 2017
0
522
(Phys.org)—The majority of the human genome is located within the nucleus. However, there is a small but important portion of DNA located within the mitochondria. This mitochondrial DNA (mtDNA) has received much attention ...
A duo of scientists at Penn State University has achieved a major milestone in understanding how genomic "dark matter" originates. This "dark matter"—called non-coding RNA—does not contain the blueprint for making proteins ...
Biotechnology
Sep 18, 2013
12
1
RNA polymerase (RNAP or RNApol) is an enzyme that produces RNA. In cells, RNAP is needed for constructing RNA chains from DNA genes as templates, a process called transcription. RNA polymerase enzymes are essential to life and are found in all organisms and many viruses. In chemical terms, RNAP is a nucleotidyl transferase that polymerizes ribonucleotides at the 3' end of an RNA transcript.
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