Aging leads to a decline in cellular fitness and loss of optimal protein function. Many age-related ailments, including Alzheimer's and Parkinson's diseases, are caused by protein aggregation, a result of errors in protein ...
Molecular & Computational biology
Jan 19, 2022
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73
Protein production (translation) is a complex process involving machinery called ribosomes. How do cells counter ribosomal destabilization leading to premature termination of translation? Scientists at Tokyo Institute of ...
Cell & Microbiology
Nov 15, 2021
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26
A new study published in Nature Communications sheds light on the molecular function of one of the enzymes with RNA helicase activity involved in the synthesis process of the large ribosome subunit. By combining biochemical, ...
Molecular & Computational biology
Nov 3, 2021
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6
All proteins in a cell are assembled by complicated molecular machines. The precursors of these ribosomes are produced in the cell nucleus and then enter the cell through the so-called nuclear pores. Researchers at the University ...
Cell & Microbiology
Oct 27, 2021
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2505
A research group led by Prof. Guang Shouhong from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences, collaborating with Prof. Feng Xuezhu from the First Affiliated Hospital of USTC, ...
Molecular & Computational biology
Sep 27, 2021
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6
A trio of researchers working at the School of Life Sciences, Tsinghua-Peking Center for Life Sciences, has chemically synthesized a mirror-image of Pfu DNA polymerase. In their paper published in the journal Nature Biotechnology, ...
St. Jude Children's Research Hospital scientists have used single-molecule fluorescence resonance energy transfer (smFRET) and cryogenic electron microscopy (cryo-EM) to capture six new structures of the ribosome and its ...
Molecular & Computational biology
Jul 8, 2021
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14
Proteins are the essence of life: they give structure to cells and organelles, catalyze metabolic reactions, build, break, tug, and pull—they carry out most of the actions that sustain a cell's existence.
Biotechnology
Jun 9, 2021
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10
According to researchers at the University of Illinois Chicago, the antibiotics used to treat common bacterial infections, like pneumonia and sinusitis, may also be used to treat human diseases, like cancer. Theoretically, ...
Cell & Microbiology
May 25, 2021
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36
Viruses require the resources of an infected cell to replicate and then infect further cells, and transfer to other individuals. One essential step in the viral life cycle is the production of new viral proteins based on ...
Molecular & Computational biology
May 13, 2021
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