Related topics: protein · messenger rna

Study offers insight into the origin of the genetic code

An analysis of enzymes that load amino acids onto transfer RNAs—an operation at the heart of protein translation—offers new insights into the evolutionary origins of the modern genetic code, researchers report. Their ...

How 'junk DNA' can control cell development

Researchers from the Gene and Stem Cell Therapy Program at Sydney's Centenary Institute have confirmed that, far from being "junk", the 97 per cent of human DNA that does not encode instructions for making proteins can play ...

A roundabout route to protein production

Proteins are typically encoded by linear strands of messenger RNA (mRNA). These mRNA molecules are translated into polypeptide chains by ribosomes, with each ribosomal read-through of the mRNA generating a single, discrete ...

The ribosome: A new target for antiprion medicines

New research results from Uppsala University, Sweden, show that the key to treating neurodegenerative prion diseases such as mad cow disease and Creutzfeldt-Jakob disease may lie in the ribosome, the protein synthesis machinery ...

Biologists simulate a cell in action

(Phys.org) —The inner workings of a cell involve hundreds of thousands of discrete molecules, engaged in a repeating cycle of interactions that sustain life.

Mimicking living cells: Synthesizing ribosomes

Synthetic biology researchers at Northwestern University, working with partners at Harvard Medical School, have for the first time synthesized ribosomes—cell structures responsible for generating all proteins and enzymes ...

This image could lead to better antibiotics

(Phys.org) —This may look like a tangle of squiggly lines, but you're actually looking at a molecular machine called a ribosome. Its job is to translate DNA sequences into proteins, the workhorse compounds that sustain ...

Study reveals key step in protein synthesis

Scientists at the University of California, Santa Cruz, have trapped the ribosome, a protein-building molecular machine essential to all life, in a key transitional state that has long eluded researchers. Now, for the first ...

Mapping translation sites in the human genome

Because of their central importance to biology, proteins have been the focus of intense research, particularly the manner in which they are produced from genetically coded templates—a process commonly known as translation. ...

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