Orchestrating development in the fly embryo

Most multicellular organisms on Earth—including you—begin as a single fertilized egg and then undergo a complex choreography of cellular growth to become a functioning adult composed of countless cells. Understanding ...

Biologists design a plug-and-play controller for gene expression

Researchers from two University of Texas System institutions have engineered biological components that can rewire genetic response pathways, creating a template for designing new cellular behaviors with wide-ranging potential ...

Overspending on defense arsenal bankrupts a plant's economy

Defend or grow? Can plants do both at the same time? Michigan State University scientists might be inching closer to answering these questions. The answers matter. They could someday help us understand natural ecosystems ...

Can you evolve while being robust?

It was long thought that DNA, together with the genes encoded in it, determined genetic destiny. But equally important is coordinating when genes are turned on and off. In fact, the regulation of gene expression defines life ...

Stem cells: Keeping differentiation in check

Researchers at the A*STAR Institute of Medical Biology (IMB) have discovered a critical checkpoint protein that controls when human embryonic stem cells (hESCs) begin to differentiate.

Proteins barge in to turn off unneeded genes

(Phys.org)—The sorcerer's apprentice started a water-carrying system, but couldn't stop it, and soon he was up to his neck in water, and trouble. Living cells have a better design: When they activate a gene, they have a ...

Controlling inflammatory and immune responses

Researchers at the IRCM, led by geneticist Dr. Jacques Drouin, recently defined the interaction between two essential proteins that control inflammation. This important breakthrough will be published in tomorrow's print edition ...

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