Gene-OFF switches tool up synthetic biology

In the quest for tomorrow's diagnostics, therapeutics, and bioproduced drugs and fine chemicals, synthetic biologists are assembling artificial networks of genes and modular regulatory elements, similar to the electronic ...

A reliable clock for your microbiome

For all the attention the human microbiome has been getting over the last few years, one aspect of such research rarely makes headlines: the difficulty of observing how it changes over time in response to various stimuli. ...

Orchestrating development in the fly embryo

Most multicellular organisms on Earth—including you—begin as a single fertilized egg and then undergo a complex choreography of cellular growth to become a functioning adult composed of countless cells. Understanding ...

Biologists design a plug-and-play controller for gene expression

Researchers from two University of Texas System institutions have engineered biological components that can rewire genetic response pathways, creating a template for designing new cellular behaviors with wide-ranging potential ...

Overspending on defense arsenal bankrupts a plant's economy

Defend or grow? Can plants do both at the same time? Michigan State University scientists might be inching closer to answering these questions. The answers matter. They could someday help us understand natural ecosystems ...

Can you evolve while being robust?

It was long thought that DNA, together with the genes encoded in it, determined genetic destiny. But equally important is coordinating when genes are turned on and off. In fact, the regulation of gene expression defines life ...

Stem cells: Keeping differentiation in check

Researchers at the A*STAR Institute of Medical Biology (IMB) have discovered a critical checkpoint protein that controls when human embryonic stem cells (hESCs) begin to differentiate.

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