Related topics: genes

Novel sex-determination mechanism revealed in mammals

In mammals, the distinction between male and female at the chromosomal level is due to the X and Y chromosomes. Typically, females have two X chromosomes (XX) while males have an X and a Y chromosome (XY). The Sry gene on ...

A study uncovers the 'grammar' behind human gene regulation

A research group at the University of Helsinki has discovered the logic that controls gene regulation in human cells. In the future, this new knowledge could be used for investigating cancers and other genetic diseases.

Illuminating dark matter in human DNA

Researchers at University of California San Diego have produced a single-cell chromatin atlas for the human genome. Chromatin is a complex of DNA and protein found in eukaryotic cells; regions of chromatin at key gene regulatory ...

The DNA regions in our brain that contribute to making us human

With only 1% difference, the human and chimpanzee protein-coding genomes are remarkably similar. Understanding the biological features that make us human is part of a fascinating and intensely debated line of research. Researchers ...

Viruses play critical role in evolution and survival of the species

As the world scrambles to control the growing COVID-19 coronavirus pandemic, new research in Nature Structural & Molecular Biology shows viruses also play a key evolutionary role in mammals' ability to reproduce and survive.

ENCODE3: Interpreting the human and mouse genomes

Scientists around the world have access to a rich trove of information through the Encyclopedia of DNA Elements (ENCODE)—annotated versions of the human and mouse genomes that are vital for interpreting their genetic codes. ...

New tool reveals DNA structures that influence disease

Disruption of certain DNA structures—called topologically associating domains, or TADs—is linked with the development of disease, including some cancers. With its newly created algorithm that quickly locates and helps ...

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