DNA 'spool' modification affects aging and longevity

Research on a modified protein around which DNA is wrapped sheds light on how gene regulation is linked to aging and longevity in nematodes, fruit flies and possibly humans.

How snakes lost a blueprint for making limbs

Snakes lost their limbs over 100 million years ago, but scientists have struggled to identify the genetic changes involved. A Cell paper publishing October 20 sheds some light on the process, describing a stretch of DNA involved ...

A study uncovers the 'grammar' behind human gene regulation

A research group at the University of Helsinki has discovered the logic that controls gene regulation in human cells. In the future, this new knowledge could be used for investigating cancers and other genetic diseases.

New insights into cooperativity in gene regulation

In a study published in Nature, Dirk Schübeler and his group at the Friedrich Miescher Institute for Biomedical Research (FMI) describe how the interplay between transcription factors and epigenetic modifications of DNA ...

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