Grainyhead, a master regulator that controls DNA access

A team led by Prof. Stein Aerts (VIB-KU Leuven) has reported how access to relevant DNA regions is orchestrated in epithelial cells. These findings shed new light on the biological mechanisms of gene regulation and open up ...

Researchers identify how eye loss occurs in blind cavefish

Loss of eye tissue in blind cavefish (Astyanax mexicanus), which occurs within a few days of their development, happens through epigenetic silencing of eye-related genes, according to a study led by the National Institutes ...

Embryonic gene regulation through mechanical forces

During embryonic development, genetic cascades control gene activity and cell differentiation. In a new publication of the journal PNAS, the team of Ulrich Technau of the Department of Molecular Evolution and Development ...

Study: How life generates new forms

When organisms change during the course of evolution, often what drives new forms is not genes themselves, but gene regulation —what turns genes on and off. A new study identifies the kind of gene regulation most likely ...

Three genes essential for cells to tell time

One family of genes allows cells to adapt to daily changes in environmental conditions by adjusting the circadian clock responsible for regular sleep-wake cycles. The new discovery by University of Tokyo scientists reveals ...

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