Bile ducts are pathways that carry hepatocyte-produced bile from the liver to the small intestine. In the human fetal liver, bile ducts are formed from bile duct epithelial cells surrounding the portal vein, and hepatocytes ...
Cell & Microbiology
Jan 9, 2024
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1
Before researchers can develop targeted drugs, they need to know exactly how a disease works. Biochemist Bert Beerkens created molecules that allow them to find out. He used caffeine as the basis for new molecules that enable ...
Biochemistry
Dec 8, 2023
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8
Depression, obesity or chronic pain—all of these disorders can be triggered or promoted by stress. In two publications, researchers at TU Darmstadt show new ways of treating stress-related diseases.
Biochemistry
Nov 10, 2023
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53
An ideal medicine for one person may prove ineffective or harmful for someone else, and predicting who could benefit from a given drug has been difficult. Now, an international team led by neuroscientist Kirill Martemyanov, ...
Cell & Microbiology
Oct 31, 2023
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119
Engineers at the University of California San Diego have developed modular nanoparticles that can be easily customized to target different biological entities such as tumors, viruses or toxins. The surface of the nanoparticles ...
Bio & Medicine
Oct 30, 2023
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57
Japanese scientist Kikunae Ikeda first proposed umami as a basic taste—in addition to sweet, sour, salty and bitter—in the early 1900s. About eight decades later, the scientific community officially agreed with him.
Cell & Microbiology
Oct 5, 2023
1
393
All over the world, huge quantities of crop protection agents are sprayed to control potato blight (Phytophthora infestans). The mechanisms of resistance of potatoes need to be better understood to make growing this crop ...
Molecular & Computational biology
Sep 11, 2023
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1
Signal transduction and perception regulates biological activities to adapt to changing environments. The Pert-Arnt-Sim domains are commonly available sensors found across diverse receptors in bacteria, eukaryotes, and archaea. ...
Wnt signaling is a well-known mode of cell-to-cell communication in multicellular biological organisms. It involves the secretion of small Wnt glycoproteins, by signaling cells, that bind to receptor proteins in the membrane ...
Molecular & Computational biology
Aug 3, 2023
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66
In a compost heap, the nematode Caenorhabditis elegans finds a richly laid table: at a length of just one millimeter, the worm feeds on bacteria that decompose organic material. It is essential that the animal avoids sunlight—and ...
Biotechnology
Aug 2, 2023
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