Newly identified compound binds to Shiga toxin to reduce its toxicity

A strain of E. coli bacteria called enterohemorrhagic E. coli (EHEC) is known to cause several gastrointestinal disorders, which include bloody diarrhea and abdominal cramps, by damaging the intestinal lining. When accompanied ...

Diphthamide is an Achilles heel shared by both plants and animals

The biomolecule diphthamide is essential for the proper formation of proteins in cells. When humans are infected with diphtheria, diphthamide is altered by the diphtheria toxin so that life-threatening complications can arise ...

Why bacterial toxins are 'fascinating machines of death'

The coronavirus pandemic is a daily reminder of the consequences brought by a successful invasion of human cells by a pathogen. As new research on bacterial toxins shows, it does not take much for these encounters to turn ...

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