Before researchers can develop targeted drugs, they need to know exactly how a disease works. Biochemist Bert Beerkens created molecules that allow them to find out. He used caffeine as the basis for new molecules that enable ...
Biochemistry
Dec 8, 2023
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8
Investigating the building blocks of biology can lead to unexpected outcomes. That's what happened when researchers at the Department of Energy's Oak Ridge National Laboratory were exploring plant genetics. Although their ...
Cell & Microbiology
Aug 1, 2023
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5
Oak Ridge National Laboratory researchers have identified specific proteins and amino acids that could control bioenergy plants' ability to identify beneficial microbes that can enhance plant growth and storage of carbon ...
Biotechnology
Mar 20, 2023
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37
A team of interdisciplinary researchers from the Institut National de la Recherche Scientifique (INRS) is hoping to identify effective COVID-19 therapeutics. With help from the Canadian Light Source (CLS) at the University ...
Biochemistry
Sep 28, 2022
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9
The initiation of the innate immune responses relies on the detection of microbes by multiple pattern recognition receptors. Among these receptors, cyclic GMP-AMP synthase (cGAS) has been identified as a major and universal ...
Cell & Microbiology
Sep 8, 2022
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4
A study published in Pharmacological Research reveals the oligomeric molecular structure of the MOR-Gal1R complex, a component present in the brain which is involved in the analgesic and addictive effects of certain opioids. ...
Biochemistry
Jul 22, 2022
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18
Proteins are like machines. For some diseases, it can be useful to turn these machine off or on when they are too active or not active enough. One way to control switching in a protein, such as a nuclear receptor, is to put ...
Molecular & Computational biology
Jun 1, 2022
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5
Researchers have identified the gene expression regulation mechanisms that drive the metamorphosis of coral from larvae that float freely in the ocean to sedentary adult reef builder adults.
Plants & Animals
Mar 10, 2022
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7
The human genome was sequenced around 20 years ago. Since then, the sequence information encoding our proteins is known—at least in principle. However, this information is not continuously stored in the individual genes, ...
Biotechnology
Jun 16, 2021
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1
Plants are constantly exposed to microbes: Pathogens that cause disease, commensals that cause no harm or benefit, and mutualists that promote plant growth or help fend off pathogens. For example, most land plants can form ...
Plants & Animals
Jun 10, 2021
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9
