New work from Carnegie's Shouling Xu and Zhiyong Wang reveals that the process of synthesizing many important master proteins in plants involves extensive modification, or "tagging" by sugars after the protein is assembled. ...
Biotechnology
Jan 30, 2017
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7
A Hokkaido University researcher has successfully developed a method to accurately manipulate gene expression by light illumination and demonstrated its usability by creating double-headed zebrafish.
Biochemistry
Jan 24, 2017
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7
(Phys.org)—A team of researchers with Massachusetts General Hospital, Harvard Medical School and the Broad Institute has developed a procedure to decode histone modifications that point out gene regulation. In their paper ...
A group of researchers led by Tomoji Mashimo, Associate Professor, Institute of Experimental Animal Sciences, Graduate School of Medicine, Osaka University and Kazuto Yoshitomi, Assistant Professor, Mouse Genomics Resource ...
Biotechnology
Mar 24, 2016
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2
DNA represents a dynamic form of information, balancing efficient storage and access requirements. Packaging approximately 1.8m of DNA into something as small as a cell nucleus is no mean feat, but unpacking it again to access ...
Biotechnology
Nov 6, 2015
1
35
The human genome encodes roughly 20,000 genes, only a few thousand more than fruit flies. The complexity of the human body, therefore, comes from far more than just the sequence of nucleotides that comprise our DNA, it arises ...
Cell & Microbiology
Jul 15, 2015
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44
Whether it is for pharmaceuticals, or imaging, or proteomics, many scientists are interested in finding better ways to chemically tweak proteins. However, proteins are chemically complex, and targeting one particular place ...
Chemical changes - also known as epigenetic modifications - to messenger RNA (mRNA) are thought to play an important role in gene expression, and have recently been found to affect biological processes such as circadian clock ...
Cell & Microbiology
Feb 25, 2015
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47
Ludwig Maximilian University of Munich researchers report the discovery of a new mechanism used by pathogenic bacteria to disable host defenses: Addition of a sugar residue at a specific position within the translation factor ...
Cell & Microbiology
Feb 18, 2015
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9
University of North Carolina scientists have created a new research tool, based on the fruit fly, to help crack the histone code. This research tool can be used to better understand the function of histone proteins, which ...
Cell & Microbiology
Feb 10, 2015
1
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